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OEM Supply China Allantoin – Povidone Iodine Manufacturers / PVP-I – Springchem

OEM Supply China Allantoin – Povidone Iodine Manufacturers / PVP-I – Springchem


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OEM Supply China Allantoin – Povidone Iodine Manufacturers / PVP-I – Springchem Detail:

Povidone Iodine / PVP-I Parameters

Introduction:

INCI CAS#
Povidone iodine  25655-41-8

Povidone (polyvinylpyrrolidone, PVP) is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs. It has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems.

Povidone has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder. Povidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents. The k number refers to the mean molecular weight of the povidone. Povidones with higher K-values (i.e., k90) are not usually given by injection due to their high molecular weights. The higher molecular weights prevent excretion by the kidneys and lead to accumulation in the body. The best-known example of povidone formulations is povidone-iodine, an important disinfectant.

Free flowing,reddish-brown powder, good stability,non-irritant, soluble in water and ethnol, safer

and easier to use. Effective in killing bacillus,viruses & epiphytes. Compatible with most surface.

Exists as free flowing,redish brown powder, non-irritant with good stability, dissolve in water and alcohol, insoluble in diethylethe and chloroform.

Specifications

Appearance Free-flowing,reddish-brown powder
Identifications A deep blue colour is produced; A light brown colour film formed which is readily dissolved in water
Available Iodine       % 9.0-12.0      
Iodine            % max 6.6
Heavy Metals    ppm max 20 (USP26/CP2005/USP31)
Sulphate Ash      % max 0.1 (USP26/CP2005/USP31)        0.025 (EP6.0)
Nitrogen Content     % 9.5-11.5 (USP26/CP2005/USP31)
pH Value( 10% in water) 1.5-5.0 (EP6.0)
Loss on Drying     % max 8.0

Package

 25KGS per cardboard drum

Period of validity

24month

Storage

Two years if stored under cool and dry conditions and well closed container

Povidone Iodine / PVP-I Application

Broad-spectrum germicidal action

*Skin and equipment disinfectant before injection or surgery.

*Anti-infection treatment for oral,gynecological,surgical,skin,etc.

*Disinfects family tableware and apparatus

*Sterilizes,disinfects in the foodstuff industry,breeding   aquatics,also prevents animal diseases.

 Povidone Iodine is one of the broad-spectrum disinfectant form human/animal health and other industries,it’s acted as 1)Surgical disinfectant for skin and equipments,2)Disinfectant for aquatics and animals,3)Microbicide for food and feed industries,4)Antiseptic for gynecological nursing products,oral care formulations.

 

Povidone Iodine / PVP-I Certificate of Analysis

Product Name: POVIDONE IODINE (PVP-I)
Properties Specifications Results
Apperance Reddish-brown or yellowish-brown Reddish-brown
Identification A,B (USP26) Confirmed
Loss on drying% ≤8.0 4.9
Residue on ignition% ≤0.1 0.02
Available iodine% 9.0~12.0 10.75
Iodide ion% ≤6.6 1.2
Nitrogen content% 9.5~11.5 9.85
Heavy metals(as Pb)PPM ≤20 <20
Conclusion This Product Meets The Requirements For USP26

 

Povidone (polyvinylpyrrolidone, PVP) is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs. It has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems.

 

Povidone has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder. Povidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents. The k number refers to the mean molecular weight of the povidone. Povidones with higher K-values (i.e., k90) are not usually given by injection due to their high molecular weights. The higher molecular weights prevent excretion by the kidneys and lead to accumulation in the body. The best-known example of povidone formulations is povidone-iodine, an important disinfectant.


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