Chlorhexidine Gluconate Solution / CHG 20%
Introduction:
| INCI | CAS# | Molecular | M.W. |
| Chlorhexidine gluconate | 18472-51-0 | C22H30Cl2N10·2C6H12O7 | 897.56 |
An almost colourless or pale-yellow transparent liquid, odorless, miscible with water, sparingly soluble in alcohol and acetone; Relative density: 1. 060 ～1.070.
Chlorhexidine gluconate, for example, is a widely-used broad-spectrum antiseptic, which has faster and longer-acting antiseptic action and capability than the iodophors.
Chlorhexidine gluconate is an antiseptic agent that has been shown to decrease microbial flora on the skin and prevent infection risk in various settings, including as a skin preparatory agent for surgical procedures and for insertion of vascular access devices, as a surgical hand scrub, and for oral hygiene.
Chlorhexidine gluconate has been shown to reduce plaque in the oral cavity, it has been shown to be effective in minimizing the septic episodes in the oral cavity when used with other chemotherapeutic agents.
Chlorhexidine The effectiveness of chlorhexidine is documented in many controlled clinical trials showing a 50% to 60% decrease in plaque, a 30% to 45% reduction in gingivitis, and a reduction in the number of oral bacteria. The efficacy of chlorhexidine stems from its ability to bind to oral tissues and slow release into the oral cavity.
Specifications
| Physical state | Colorless to Pale Yellow Clear Liquid |
| Melting point/ freezing point | 134ºC |
| Boiling point or initial boiling point and boiling range | 699.3ºC at 760 mmHg |
| Lower and upper explosion limit / flammability limit | no data available |
| Flash point | 376.7ºC |
| Vapour pressure | 0mmHg at 25°C |
| Density and/or relative density | 1.06g/mLat 25°C(lit.) |
Package
plastic bucket, 25kg/ package
Period of validity
12month
Storage
It should be kept in cool, dark and dry place, stored in sealed containers.
It is a disinfect and antiseptic medicine; bactericide, strong function of broad-spectrum bacteriostasis, sterilization ; take effective for kill gram-positive bacteria gram-negative bacteria; used for disinfecting hands, skin, washing wound.
| Product Name | Chlorhexidine Digluconate 20% | |
| Inspection Standard | According to the China Pharmacopeia ,Secunda Partes,2015. | |
| Items | Specifications | Results |
|
Character |
Colorless to light yellow almost clarify and slightly sticky liquid,odourless or almost odourless. | Light yellow and almost clarify slightly sticky liquid,odourless. |
| The product is miscible with water,dissolved in ethanol or propanol. | Confirm | |
| Relative Density | 1.050~1.070 | 1.058 |
| Identify | ①、②、③ should be positive reaction. | Confirm |
| Acidity | pH 5.5~7.0 | pH=6.5 |
| P-chloroaniline | Should confirm the rule. | Confirm |
| Related Substance | Should confirm the rule. | Confirm |
| Residue on ignition | ≤0.1% | 0.01% |
| Assay Chlorhexidine Gluconate | 19.0%~21.0%（g/ml） | 20.1（g/ml） |
| Conclusion | Testing according to the China Pharmacopeia,Secunda Partes,2015.
Result:Confirm |
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